Bacteria evolve… So do our models
Bacteria evolve… So do our models
From a pathogenic strain
to a validated phage shortlist
in days instead of years
From a pathogenic strain to a validated phage shortlist in days
Bacteria change faster than traditional drug discovery can follow.
Bacteria change faster than traditional drug discovery can follow.
Phagos isolates phages from environmental samples, sequences both phages and target bacteria, predicts their interactions with proprietary AI models, validates candidates at the bench, manufactures them and follows their performance in real-world conditions. What is learned in one iteration serves the next.
Phagos isolates phages from environmental samples, sequences both phages and target bacteria, predicts their interactions with proprietary AI models, validates candidates at the bench, manufactures them and follows their performance in real-world conditions. What is learned in one iteration serves the next.
THE PLATFORM
How it works
One question drives the loop: which phages in the collection will kill this strain, and which handful should the lab test first?
01.DIAGNOSE
02.IDENTIFY
03.DESIGN
04.TEST
05.DEPLOY
DIAGNOSE
IDENTIFY
DESIGN
TEST
DEPLOY
PHAGOS
PLATFORM
DIAGNOSE
A pathogenic bacterial strain comes in. We sequence it and place it among the strains we already know.
DIAGNOSE
IDENTIFY
DESIGN
TEST
DEPLOY
PHAGOS
PLATFORM
DIAGNOSE
A pathogenic bacterial strain comes in. We sequence it and place it among the strains we already know.
One of the world’s largest characterized phage collections
One of the world’s largest characterized phage collections
One of the world’s largest characterized phage collections
Public databases mostly hold genomes. Ours pairs each genome with lab results: which phage kills which strain, measured under the same standardized conditions. That is the data our models learn from.
Every week, we isolate new phages from environmental samples. Each one is sequenced and tested before it enters the collection.
Public databases mostly hold genomes. Ours also records which phage kills which strain, under the same conditions. We isolate new phages from environmental samples every week, and each one is sequenced and tested before it joins.
What is a phage?
What makes it work
What makes it work
What makes it work
01
Our own data
Every interaction our models learn from was tested in our laboratory, under the same conditions.
01
Our own data
Every interaction our models learn from was tested in our laboratory, under the same conditions.
02
Both genomes
We sequence both phages and target bacteria, so the models see both sides of every interaction.
02
Both genomes
We sequence both phages and target bacteria, so the models see both sides of every interaction.
03
Verdicts from the bench
A phagogram returns a physical answer within days. Hits and misses both become training data.
03
Verdicts from the bench
A phagogram returns a physical answer within days. Hits and misses both become training data.
04
Real-world outcomes
Performance in real-world conditions feeds back into the data. Few organisations can supply that kind of verifiable signal at scale.
04
Real-world outcomes
Performance in real-world conditions feeds back into the data. Few organisations can supply that kind of verifiable signal at scale.
05
Inspectable evidence
Assays, predictions and field outcomes stay separate and inspectable, so every recommendation can be checked.
05
Inspectable evidence
Assays, predictions and field outcomes stay separate and inspectable, so every recommendation can be checked.
06
Designed to go further
Animal health is where the loop was built and proven. The same engine is designed to go further, starting with human health.
06
Designed to go further
Animal health is where the loop was built and proven. The same engine is designed to go further, starting with human health.